WebOct 3, 2024 · In this review, we summarize the role of primary cilium specifically with regard to GBM, where there is evidence postulating it as a critical mediator of GBM tumorigenesis and progression. This opens the way to the application of cilia-targeted therapies ('ciliotherapy') as a new approach in the fight against this devastating tumour. WebFeb 1, 2024 · Request PDF Mechanosensory and Chemosensory Primary Cilia in Ciliopathy and Ciliotherapy "Over the past few decades, we have been able to integrate mechanobiology into the molecular basis of ...
Ciliotherapy: a novel intervention in polycystic kidney disease.
WebApr 15, 2024 · Microenvironment has directly implicated in an early stage of ciliopathy. Thus, the next nano-material advances for a cilia-targeted therapy or ciliotherapy are a desirable approach to treat ciliopathies. We report here that we have generated cilia-targeted iron oxide (Fe 2 O 3) nanoparticles that offer a new prototype in ciliotherapy. Live ... WebMar 12, 2024 · We devised the iron oxide nanoparticle (NP)-based technology for ciliotherapy. Live imaging confirmed that the CT-Fe2O3-NPs specifically targeted … import user ad csv
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WebPersonalized Nanotherapy by Specifically Targeting Cell Organelles To Improve Vascular Hypertension. Nano Lett. 2024 Feb 13;19(2):904-914. Ciliotherapy: Remote Control of Primary Cilia Movement and Function by Magnetic Nanoparticles.ACS Nano WebCiliotherapy: Remote Control of Primary Cilia Movement and Function by Magnetic Nanoparticles WebMar 1, 2014 · Methods and Results. In the present studies, our in vitro analyses refined fenoldopam as an equipotent and more specific dopaminergic agonist to regulate cilia length and function. Our in vivo studies indicated that fenoldopam increased cilia length and serum NO thereby reducing blood pressure in a PKD mouse model. Our crossover, multicenter, … litewave kick s carbon review