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WebFeb 18, 2024 · Some treatment options are available over-the-counter (OTC), and others are available with a prescription. Deagreez/iStock via Getty Images Cold sores — also called fever blisters — are caused by a virus called herpes simplex virus type 1 (HSV-1). WebAug 23, 2024 · SOURCES: WebMD Medical News: "Genital Herpes Treatment Cuts Spread." CDC. Corey, L. NEJM, 2004. WebSep 12, 2024 · Most cold sore medicines are affordable, over-the-counter solutions that cost between $10 and $20. Our least expensive product was Lysine+ Lip Treatment at $12. We also considered non-OTC treatment, Virulite, … bromberg\u0027s the summit